Ccl3 | C-C motif chemokine ligand 3

GeneMGI:98260Synonyms: MIP1-alpha, MIP-1alpha, +8 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating total protein level1 supporting datasetCcl3em1(IMPC)HhomozygoteEarly adult5.53x10-7 
decreased circulating serum albumin level1 supporting datasetCcl3em1(IMPC)HhomozygoteEarly adult3.06x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccl3em1(IMPC)HInter-exon deletionmouse
Ccl3em2(IMPC)HInter-exon deletionmouse
Ccl3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Ccl3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ccl3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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