Sag | S-antigen, retina and pineal gland (arrestin)

GeneMGI:98227Synonyms: rod arrestin, A930001K18Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Vision/eye

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating calcium level1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult3.15x10-8 
iris synechia1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult8.4x10-5 
decreased circulating fructosamine level1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult9.45x10-5 
decreased circulating HDL cholesterol level1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult7.66x10-5 
increased lean body mass1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult4.4x10-7 
decreased total body fat amount1 supporting datasetSagtm1a(EUCOMM)WtsihomozygoteEarly adult1.42x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sagtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Sagtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Sagtm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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