Rras | related RAS viral (r-ras) oncogene

GeneMGI:98179Synonyms: Rras1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating triglyceride level1 supporting datasetRrasem1(IMPC)HhomozygoteEarly adult7.1x10-6 
decreased circulating calcium level1 supporting datasetRrasem1(IMPC)HhomozygoteEarly adult1x10-6 
increased circulating serum albumin level1 supporting datasetRrasem1(IMPC)HhomozygoteEarly adult4.26x10-5 
increased grip strength2 supporting datasetsRrasem1(IMPC)HhomozygoteEarly adult5.35x10-5 
decreased fasting circulating glucose level1 supporting datasetRrasem1(IMPC)HhomozygoteEarly adult3.56x10-7 
prolonged QRS complex duration1 supporting datasetRrasem1(IMPC)HhomozygoteEarly adult4.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rrasem1(IMPC)HExon Deletionmouse
Rrastm111841(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
KO first allele (reporter-tagged insertion with conditional potential)ES Cell
mouse

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