Rnps1 | RNA binding protein with serine rich domain 1

GeneMGI:97960

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	3.3x10^-5
abnormal vitreous body morphology	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	7.87x10^-5
abnormal iris morphology	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	4.06x10^-9
irregularly shaped pupil	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	9.96x10^-8
decreased fasting circulating glucose level	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	8.13x10^-5
increased mean corpuscular volume	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	2x10^-6
increased startle reflex	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.14x10^-7
increased mean corpuscular hemoglobin	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	4.88x10^-5
abnormal cornea morphology	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.15x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Rnps1^{em1(IMPC)Hmgu}	heterozygote	Early adult	3.43x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnps1.

Associated images

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Histopathology

There is no histopathology data found for Rnps1.

IMPC related publications

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External links

No external links available for Rnps1.

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*Rnps1^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Rnps1^{tm188337(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Rnps1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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