Slc20a2 | solute carrier family 20, member 2

GeneMGI:97851Synonyms: PiT-2, Ram-1, +3 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Craniofacial Mortality/aging

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:25Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



abnormal vocalization	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.06x10^-5
abnormal lens morphology	3 supporting datasets	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.66x10^-7
abnormal lens morphology	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.04x10^-13
increased grip strength	2 supporting datasets	Slc20a2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.96x10^-6
cataract	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.04x10^-13
impaired glucose tolerance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.16x10^-5
decreased bone mineral density	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.14x10^-6
abnormal motor coordination/balance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.23x10^-6
increased total body fat amount	2 supporting datasets	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.4x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc20a2.

Associated images

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Histopathology

There is no histopathology data found for Slc20a2.

IMPC related publications

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External links

No external links available for Slc20a2.

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*Slc20a2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Slc20a2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Slc20a2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc20a2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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