Slc20a2 | solute carrier family 20, member 2

GeneMGI:97851Synonyms: PiT-2, Ram-1, +3 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Skeleton Craniofacial Mortality/aging

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:25Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



abnormal vocalization	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.06x10^-5
abnormal lens morphology	3 supporting datasets	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.66x10^-7
abnormal lens morphology	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.04x10^-13
increased grip strength	2 supporting datasets	Slc20a2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.96x10^-6
cataract	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.04x10^-13
impaired glucose tolerance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.16x10^-5
decreased bone mineral density	1 supporting dataset	Slc20a2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.14x10^-6
abnormal motor coordination/balance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.23x10^-6
increased total body fat amount	2 supporting datasets	Slc20a2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.4x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Slc20a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Slc20a2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Slc20a2.

IMPC related publications

Loading...

External links

No external links available for Slc20a2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Slc20a2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Slc20a2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc20a2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc20a2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes