Rab1a | RAB1A, member RAS oncogene family

GeneMGI:97842Synonyms: Rab-1, Rab1, +3 more

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Integument Mortality/aging

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Rab1a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal vibrissa morphology	1 supporting dataset	Rab1a^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rab1a.

Associated images

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Histopathology

There is no histopathology data found for Rab1a.

IMPC related publications

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External links

No external links available for Rab1a.

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*Rab1a^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Rab1a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rab1a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rab1a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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