Pygm | muscle glycogen phosphorylase

GeneMGI:97830Synonyms: PG

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating calcium level	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	4.91x10^-13
decreased grip strength	2 supporting datasets	Pygm^em1(IMPC)J	homozygote	Early adult	8.99x10^-11
increased circulating aspartate transaminase level	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	8.91x10^-90
prolonged RR interval	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	1.12x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	4.89x10^-7
decreased bone mineral content	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	9.66x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	1.24x10^-5
decreased locomotor activity	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	7.51x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Pygm^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pygm.

Associated images

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Histopathology

There is no histopathology data found for Pygm.

IMPC related publications

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External links

No external links available for Pygm.

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*Pygm^em1(IMPC)J*	Exon Deletion	‌	mouse
*Pygm^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pygm^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pygm^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pygm^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pygm^{tm45980(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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