Ptpra | protein tyrosine phosphatase receptor type A

GeneMGI:97808Synonyms: PTPalpha, RPTPalpha, +3 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Hematopoietic system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetPtpratm1b(EUCOMM)HmguhomozygoteEarly adult1.14x10-7 
increased mean corpuscular hemoglobin1 supporting datasetPtpratm1b(EUCOMM)HmguhomozygoteEarly adult6.99x10-5 
decreased prepulse inhibition2 supporting datasetsPtpratm1b(EUCOMM)HmguhomozygoteEarly adult9.86x10-6 
decreased grip strength1 supporting datasetPtpratm1b(EUCOMM)HmguhomozygoteEarly adult4.77x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Ptpratm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ptpratm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ptpratm28617(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter