Ptma | prothymosin alpha

GeneMGI:97803Synonyms: Thym

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
58Embryo tissues

Phenotypes

preweaning lethality, complete penetrance2 supporting datasetsPtmatm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
cornea opacity1 supporting datasetPtmatm1.1(KOMP)VlcgheterozygoteEarly adult1.22x10-8 
persistence of hyaloid vascular system1 supporting datasetPtmatm1.1(KOMP)VlcgheterozygoteEarly adult1.19x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptmatm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ptmatm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ptmatm404304(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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