Pth1r | parathyroid hormone 1 receptor

GeneMGI:97801Synonyms: PPR, PTH1R, +3 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Behavior/neurological Skeleton Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased total body fat amount	1 supporting dataset	Pth1r^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	9.48x10^-5
decreased bone mineral content	1 supporting dataset	Pth1r^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	1.84x10^-6
increased grip strength	1 supporting dataset	Pth1r^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	2.92x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Pth1r^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Pth1r^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	2.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pth1r.

Associated images

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Histopathology

There is no histopathology data found for Pth1r.

IMPC related publications

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External links

No external links available for Pth1r.

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*Pth1r^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Pth1r^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Pth1r^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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