Prim1 | DNA primase, p49 subunit
GeneMGI:97757
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 4 supporting datasets | Prim1em1(IMPC)J | heterozygote | Early adult | 2.58x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Prim1em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Prim1em1(IMPC)J | homozygote | Early adult | N/A * |
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Human diseases caused by Prim1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Prim1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Prim1em1(IMPC)J | Exon Deletion | | mouse |
| Prim1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Prim1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Prim1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Prim1tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Prim1tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |