Plk1 | polo like kinase 1

GeneMGI:97621Synonyms: Plk, STPK13

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

18 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

29Embryo tissues

Phenotypes

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Plk1^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Plk1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Plk1^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plk1.

Associated images

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Histopathology

There is no histopathology data found for Plk1.

IMPC related publications

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External links

No external links available for Plk1.

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*Plk1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Plk1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Plk1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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