Pgm1 | phosphoglucomutase 1

GeneMGI:97565Synonyms: 2610020G18Rik, Pgm2, +2 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Nervous system Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal vocalization	1 supporting dataset	Pgm1^em1(IMPC)J	heterozygote	Early adult	2.42x10^-10
embryonic lethality prior to tooth bud stage	1 supporting dataset	Pgm1^em1(IMPC)Bay	homozygote	E12.5	N/A ^*
abnormal coat appearance	1 supporting dataset	Pgm1^em1(IMPC)J	heterozygote	Early adult	2.22x10^-6
abnormal forebrain development	1 supporting dataset	Pgm1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
decreased locomotor activity	1 supporting dataset	Pgm1^em1(IMPC)Bay	heterozygote	Early adult	5.23x10^-5
abnormal embryo size	1 supporting dataset	Pgm1^em1(IMPC)J	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Pgm1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Pgm1^em1(IMPC)J	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	2 supporting datasets	Pgm1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Pgm1^em1(IMPC)J	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pgm1.

Associated images

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Histopathology

There is no histopathology data found for Pgm1.

IMPC related publications

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External links

No external links available for Pgm1.

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*Pgm1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Pgm1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Pgm1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pgm1^{tm41296(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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