Prf1 | perforin 1 (pore forming protein)
Physiological systems
21 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Hematopoietic system
20 No significant impact
3 Not tested
Data collections
Gene metrics:1Significant phenotypes
6Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Prf1tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.97x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
External links
No external links available for Prf1.
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| Prf1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Prf1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Prf1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Prf1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |