Prf1 | perforin 1 (pore forming protein)

GeneMGI:97551Synonyms: Pfp, Pfn, +2 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Hematopoietic system

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

6Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



decreased mean corpuscular hemoglobin concentration	1 supporting dataset		Prf1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult		2.97x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prf1.

Associated images

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Histopathology

There is no histopathology data found for Prf1.

IMPC related publications

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External links

No external links available for Prf1.

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*Prf1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Prf1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Prf1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prf1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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