Pdgfrb | platelet derived growth factor receptor, beta polypeptide
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Growth/size/body region Cardiovascular system Mortality/aging
14 No significant impact
4 Not tested
Gene metrics:5Significant phenotypes
12Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased circulating triglyceride level | 1 supporting dataset | Pdgfrbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.19x10-5 | ||
| enlarged heart | 1 supporting dataset | Pdgfrbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| abnormal seminal vesicle morphology | 1 supporting dataset | Pdgfrbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pdgfrbtm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased circulating fructosamine level | 1 supporting dataset | Pdgfrbtm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.56x10-6 |
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External links
No external links available for Pdgfrb.
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| Pdgfrbtm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Pdgfrbtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Pdgfrbtm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Pdgfrbtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pdgfrbtm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pdgfrbtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |