Pde6a | phosphodiesterase 6A, cGMP-specific, rod, alpha

GeneMGI:97524Synonyms: Pdea

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Vision/eye

18 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/ hair morphology1 supporting datasetPde6aem2(IMPC)MbphomozygoteEarly adult1.72x10-6 
abnormal eye morphology1 supporting datasetPde6aem1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating phosphate level1 supporting datasetPde6aem1(IMPC)MbphomozygoteEarly adult2.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pde6aem1(IMPC)MbpExon Deletionmouse
Pde6aem2(IMPC)MbpIndelmouse

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