Pam | peptidylglycine alpha-amidating monooxygenase

GeneMGI:97475Synonyms: PHM

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Pam^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Pam^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.48x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pam.

Associated images

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Histopathology

There is no histopathology data found for Pam.

IMPC related publications

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External links

No external links available for Pam.

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*Pam^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Pam^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pam^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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