Osbp | oxysterol binding protein
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Integument Hematopoietic system Skeleton Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal sternum morphology | 1 supporting dataset | Osbpem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Osbpem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Osbpem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Osbpem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Osbpem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Osbpem1(IMPC)Tcp | heterozygote | Early adult | 1.6x10-5 |
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External links
No external links available for Osbp.
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| Osbpem1(IMPC)Tcp | Exon Deletion | | mouse |
| Osbptm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Osbptm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Osbptm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |