Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Nervous system Skeleton Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| decreased prepulse inhibition | 1 supporting dataset | Ntrk2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.92x10-6 | ||
| abnormal rib morphology | 1 supporting dataset | Ntrk2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.22x10-5 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Ntrk2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.98x10-5 | ||
| increased lean body mass | 1 supporting dataset | Ntrk2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.21x10-6 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ntrk2tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Ntrk2.
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| Ntrk2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Ntrk2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ntrk2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ntrk2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |