Nos2 | nitric oxide synthase 2, inducible

GeneMGI:97361Synonyms: NOS-II, Nos2a, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity1 supporting datasetNos2em1(IMPC)BayhomozygoteEarly adult9.32x10-5 
abnormal eye anterior chamber depth1 supporting datasetNos2em1(IMPC)BayhomozygoteEarly adult1.43x10-6 
decreased thigmotaxis2 supporting datasetsNos2em1(IMPC)BayhomozygoteEarly adult4.91x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nos2em1(IMPC)BayExon Deletionmouse
Nos2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Nos2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Nos2tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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