Nkx2-6 | NK2 homeobox 6

GeneMGI:97351Synonyms: Nkx2.6, Tix, +2 more

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating potassium level1 supporting datasetNkx2-6em1(IMPC)HhomozygoteEarly adult3.71x10-5 
increased circulating alanine transaminase level1 supporting datasetNkx2-6em1(IMPC)HhomozygoteEarly adult2.8x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Nkx2-6em1(IMPC)HIntra-exon deletionmouse
Nkx2-6em2(IMPC)HIntra-exon deletionmouse
Nkx2-6tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
Nkx2-6tm1.1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)ES Cell
Nkx2-6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nkx2-6tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Nkx2-6tm2(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter