Nedd1 | neural precursor cell expressed, developmentally down-regulated gene 1

GeneMGI:97293

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Hematopoietic system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Nedd1^em1(IMPC)H	homozygote	E9.5	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Nedd1^em1(IMPC)H	heterozygote	Early adult	1.09x10^-5
decreased circulating calcium level	1 supporting dataset	Nedd1^em1(IMPC)H	heterozygote	Early adult	6.33x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Nedd1^em1(IMPC)H	homozygote	Early adult	N/A ^*
increased circulating potassium level	1 supporting dataset	Nedd1^em1(IMPC)H	heterozygote	Early adult	7.03x10^-5
increased eosinophil cell number	1 supporting dataset	Nedd1^em1(IMPC)H	heterozygote	Early adult	2.29x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Nedd1^em1(IMPC)H	heterozygote	Early adult	2.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nedd1.

Associated images

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Histopathology

There is no histopathology data found for Nedd1.

IMPC related publications

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External links

No external links available for Nedd1.

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*Nedd1^em1(IMPC)H*	Exon Deletion	‌	mouse
*Nedd1^em2(IMPC)H*	Exon Deletion	‌	mouse

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