Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow

GeneMGI:97272Synonyms: MLC-2v, MLC-2, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased circulating alkaline phosphatase level	1 supporting dataset	Myl2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.07x10^-6
absent vibrissae	1 supporting dataset	Myl2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.3x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Myl2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Myl2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Myl2.

Associated images

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Histopathology

There is no histopathology data found for Myl2.

IMPC related publications

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External links

No external links available for Myl2.

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*Myl2^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Myl2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Myl2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Myl2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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