Myl4 | myosin, light polypeptide 4

GeneMGI:97267Synonyms: MLC1a, Myla, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased IgG3 level1 supporting datasetMyl4tm1a(EUCOMM)WtsihomozygoteEarly adult5.67x10-8 
decreased IgM level1 supporting datasetMyl4tm1a(EUCOMM)WtsihomozygoteEarly adult4.8x10-5 
increased circulating iron level1 supporting datasetMyl4tm1a(EUCOMM)WtsihomozygoteEarly adult3.72x10-5 
decreased IgA level1 supporting datasetMyl4tm1a(EUCOMM)WtsihomozygoteEarly adult1.64x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Myl4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Myl4tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Myl4tm47401(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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