Mx1 | MX dynamin-like GTPase 1
Physiological systems
20 / 24 physiological systems tested
20 No significant impact
4 Not tested
Data collections
Gene metrics:0Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | n/a | 0.19% (1/533) |
| blood vessel | heterozygote | n/a | 0% (0/2) | 0% (0/173) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | n/a | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | n/a | 0.41% (2/491) |
Human diseases caused by Mx1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Mx1.
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| Mx1tm1.1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | ES Cell |
| Mx1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Mx1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Mx1tm39033(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |