Mdh1 | malate dehydrogenase 1, NAD (soluble)

GeneMGI:97051Synonyms: MDH-s, B230377B03Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Behavior/neurological Mortality/aging Cardiovascular system Craniofacial

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



thick ventricular wall	1 supporting dataset	Mdh1^em1(IMPC)Bay	heterozygote	Early adult	8.76x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Mdh1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Mdh1^em1(IMPC)Bay	homozygote	E12.5	N/A ^*
abnormal pharyngeal arch morphology	1 supporting dataset	Mdh1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
decreased exploration in new environment	1 supporting dataset	Mdh1^em1(IMPC)Bay	heterozygote	Early adult	1.55x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mdh1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mdh1.

IMPC related publications

Loading...

External links

No external links available for Mdh1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mdh1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Mdh1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Mdh1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mdh1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mdh1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Mdh1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mdh1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mdh1^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes