Mmp2 | matrix metallopeptidase 2
Physiological systems
21 / 24 physiological systems tested
12 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Nervous system Vision/eye Hematopoietic system Skeleton Cardiovascular system Renal/urinary system
9 No significant impact
3 Not tested
Data collections
Gene metrics:19Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal bone structure | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Early adult | 1.13x10-10 | ||
abnormal seminal vesicle morphology | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
decreased prepulse inhibition | 2 supporting datasets | Mmp2em1(IMPC)Mbp | homozygote | Early adult | 3.97x10-5 | ||
abnormal spleen morphology | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
enlarged stomach | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
increased heart rate | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | 7.33x10-5 | ||
abnormal skin morphology | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
enlarged spleen | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
enlarged lymph nodes | 1 supporting dataset | Mmp2em1(IMPC)Mbp | homozygote | Late adult | N/A * |
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External links
No external links available for Mmp2.
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Mmp2em1(IMPC)Mbp | Exon Deletion | | mouse |