Rab8a | RAB8A, member RAS oncogene family

GeneMGI:96960Synonyms: Mel

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength4 supporting datasetsRab8aem1(IMPC)JheterozygoteEarly adult2.09x10-7 
decreased lean body mass1 supporting datasetRab8aem1(IMPC)JheterozygoteEarly adult3.26x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab8aem1(IMPC)JExon Deletionmouse
Rab8atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rab8atm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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