Anxa1 | annexin A1

GeneMGI:96819Synonyms: Lpc1, Lpc-1, +3 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Respiratory system Hematopoietic system Cardiovascular system Renal/urinary system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	2 supporting datasets	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased airway resistance	2 supporting datasets	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.43x10^-8
abnormal heart morphology	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Anxa1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Anxa1.

Associated images

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Histopathology

There is no histopathology data found for Anxa1.

IMPC related publications

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External links

No external links available for Anxa1.

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*Anxa1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Anxa1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Anxa1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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