Loricrin | loricrin cornified envelope precursor protein
GeneMGI:96816
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Liver/biliary system Hematopoietic system Mortality/aging Renal/urinary system
11 No significant impact
3 Not tested
Data collections
Gene metrics:13Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| abnormal testis morphology | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal vibrissa morphology | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.82x10-9 | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Loricrintm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | homozygote | Early adult | 2.99x10-6 | ||
| increased kidney weight | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | homozygote | Early adult | 4.19x10-8 | ||
| abnormal uterus morphology | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Loricrintm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
No external links available for Loricrin.
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