Lipe | lipase, hormone sensitive

GeneMGI:96790Synonyms: HSL, 4933403G17Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Growth/size/body region Behavior/neurological Skeleton Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	4 supporting datasets	Lipe^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.89x10^-6
increased circulating insulin level	1 supporting dataset	Lipe^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.73x10^-7
increased kidney weight	1 supporting dataset	Lipe^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.3x10^-5
increased bone mineral density	1 supporting dataset	Lipe^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.86x10^-6
male infertility	1 supporting dataset	Lipe^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lipe.

Associated images

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Histopathology

There is no histopathology data found for Lipe.

IMPC related publications

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External links

No external links available for Lipe.

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*Lipe^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lipe^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lipe^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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