Lhcgr | luteinizing hormone/choriogonadotropin receptor

GeneMGI:96783Synonyms: LH-R, Gpcr19-rs1, +1 more

Physiological systems

13 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Digestive/alimentary Nervous system Respiratory system Liver/biliary system Hematopoietic system Cardiovascular system

5 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small liver1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
increased lymphocyte cell number1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adult8x10-6 
small spleen1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
increased leukocyte cell number1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adult1.08x10-11 
decreased brain size1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
small thymus1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
small heart1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
thrombocytopenia1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adult6.48x10-6 
decreased mean corpuscular volume1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adult8.27x10-5 
small stomach1 supporting datasetLhcgrtm1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lhcgrtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse

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