Lamp1 | lysosomal-associated membrane protein 1
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small spleen | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | 5.03x10-5 | ||
| enlarged testis | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased leukocyte cell number | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | 4.34x10-12 | ||
| increased lymphocyte cell number | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | 4.96x10-15 | ||
| increased circulating phosphate level | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | 3.23x10-6 | ||
| small adrenal glands | 1 supporting dataset | Lamp1em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Lamp1.
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| Lamp1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Lamp1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Lamp1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |