Krt17 | keratin 17

GeneMGI:96691Synonyms: K17, Krt1-17

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system

13 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
51Embryo tissues

Phenotypes

increased hemoglobin content1 supporting datasetKrt17tm1.1(KOMP)VlcgheterozygoteEarly adult5.68x10-5 
increased circulating alanine transaminase level1 supporting datasetKrt17tm1.1(KOMP)VlcgheterozygoteEarly adult1.05x10-5 
increased heart weight1 supporting datasetKrt17tm1.1(KOMP)VlcgheterozygoteEarly adult5.88x10-7 
decreased hematocrit1 supporting datasetKrt17tm1.1(KOMP)VlcgheterozygoteEarly adult5.98x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Krt17tm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Krt17tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Krt17tm1.1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)ES Cell
Krt17tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Krt17tm112116(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Krt17tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Krt17tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Krt17tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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