Kin | Kin17 DNA and RNA binding protein

GeneMGI:96676Synonyms: Kin17, antigenic determinant of rec-A protein

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetKinem1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating calcium level1 supporting datasetKinem1(IMPC)JheterozygoteEarly adult3.74x10-5 
increased heart rate1 supporting datasetKinem1(IMPC)JheterozygoteEarly adult4.84x10-5 
embryonic lethality prior to organogenesis1 supporting datasetKinem1(IMPC)JhomozygoteE9.5N/A * 
shortened RR interval1 supporting datasetKinem1(IMPC)JheterozygoteEarly adult4.24x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kinem1(IMPC)JExon Deletionmouse
Kintm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Kintm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kintm34030(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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