Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2

GeneMGI:96659Synonyms: Kca1-2, Mk-2, +2 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetKcna2em1(IMPC)HheterozygoteEarly adult1.06x10-5 
preweaning lethality, complete penetrance1 supporting datasetKcna2em1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Kcna2em1(IMPC)HIntra-exon deletionmouse
Kcna2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Kcna2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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