Jun | jun proto-oncogene

GeneMGI:96646Synonyms: Junc, c-jun

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Embryo Growth/size/body region Nervous system Vision/eye Behavior/neurological Mortality/aging Craniofacial Cardiovascular system

12 No significant impact

2 Not tested

Gene metrics:14Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology2 supporting datasetsJunem1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetJunem1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal blood vessel morphology1 supporting datasetJunem1(IMPC)MbphomozygoteE15.5N/A * 
edema1 supporting datasetJunem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal craniofacial morphology1 supporting datasetJunem1(IMPC)MbpheterozygoteE15.5N/A * 
anophthalmia1 supporting datasetJunem1(IMPC)MbpheterozygoteEarly adultN/A * 
abnormal neural tube morphology1 supporting datasetJunem1(IMPC)MbphomozygoteE9.5N/A * 
edema1 supporting datasetJunem1(IMPC)MbpheterozygoteE15.5N/A * 
abnormal placenta morphology1 supporting datasetJunem1(IMPC)MbphomozygoteE15.5N/A * 
enlarged lymph nodes1 supporting datasetJunem1(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Junem1(IMPC)MbpWhole-gene deletionmouse
Juntm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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