Itk | IL2 inducible T cell kinase

GeneMGI:96621Synonyms: Tcsk, Emt, +1 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:1Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetItkem1(IMPC)MbphomozygoteEarly adult1.87x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Itkem1(IMPC)MbpExon Deletionmouse
Itktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Itktm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Itktm33784(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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