Itgal | integrin alpha L

GeneMGI:96606Synonyms: Ly-21, LFA-1, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Itgal^em1(IMPC)H	homozygote	Early adult	9.9x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Itgal^em1(IMPC)H	homozygote	Early adult	9.04x10^-7
increased spleen weight	1 supporting dataset	Itgal^em1(IMPC)H	homozygote	Early adult	7.89x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Itgal.

Associated images

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Histopathology

There is no histopathology data found for Itgal.

IMPC related publications

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External links

No external links available for Itgal.

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*Itgal^em1(IMPC)H*	Inter-exon deletion	‌	mouse
*Itgal^em2(IMPC)H*	Inter-exon deletion	‌	mouse

My Genes