Itga3 | integrin alpha 3

GeneMGI:96602Synonyms: VLA-3 alpha 3, alpha3-integrin

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Craniofacial Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal placenta size	1 supporting dataset	Itga3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Itga3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Itga3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Itga3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Itga3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Itga3.

Associated images

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Histopathology

There is no histopathology data found for Itga3.

IMPC related publications

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External links

No external links available for Itga3.

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*Itga3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Itga3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Itga3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Itga3^{tm51121(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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