Il9r | interleukin 9 receptor

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Liver/biliary system Behavior/neurological Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small kidney1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal behavior1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adult1.22x10-10 
decreased thigmotaxis2 supporting datasetsIl9rem1(IMPC)MbphomozygoteEarly adult1.1x10-10 
abnormal retina morphology1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adult3.47x10-5 
decreased anxiety-related response1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adult3.28x10-9 
cataract1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adult1.39x10-5 
small liver1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetIl9rem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il9rem1(IMPC)MbpExon Deletionmouse
Il9rtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Il9rtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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