Il3 | interleukin 3

GeneMGI:96552Synonyms: Csfmu, Il-3, +4 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Reproductive system Skeleton

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

female infertility1 supporting datasetIl3tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
male infertility1 supporting datasetIl3tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
decreased bone mineral content1 supporting datasetIl3tm1.1(KOMP)MbphomozygoteEarly adult9.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Il3tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Il3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Il3tm432146(L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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