Il1r1 | interleukin 1 receptor, type I

GeneMGI:96545Synonyms: Il1r-1, IL-1 receptor alpha chain, +3 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
cataract1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adult6.86x10-5 
abnormal heart morphology1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased kidney weight1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adult9.39x10-5 
enlarged kidney1 supporting datasetIl1r1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Il1r1em1(IMPC)CcpczIntra-exon deletionmouse
Il1r1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Il1r1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter