Il12a | interleukin 12a

GeneMGI:96539Synonyms: IL-12p35, p35

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



vertebral fusion	1 supporting dataset	Il12a^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.22x10^-7
increased circulating HDL cholesterol level	1 supporting dataset	Il12a^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il12a.

Associated images

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Histopathology

There is no histopathology data found for Il12a.

IMPC related publications

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External links

No external links available for Il12a.

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*Il12a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Il12a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Il12a^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Il12a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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