Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

GeneMGI:96534Synonyms: Ii, CLIP

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased neutrophil cell number	2 supporting datasets	Cd74^em1(IMPC)H	homozygote	Early adult	6.03x10^-21
increased eosinophil cell number	1 supporting dataset	Cd74^em1(IMPC)H	homozygote	Early adult	8.35x10^-5
decreased lymphocyte cell number	3 supporting datasets	Cd74^em1(IMPC)H	homozygote	Early adult	4.91x10^-26
increased monocyte cell number	1 supporting dataset	Cd74^em1(IMPC)H	homozygote	Early adult	1.68x10^-13

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cd74.

Associated images

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Histopathology

There is no histopathology data found for Cd74.

IMPC related publications

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External links

No external links available for Cd74.

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*Cd74^em1(IMPC)H*	Exon Deletion	‌	mouse
*Cd74^em2(IMPC)H*	Exon Deletion	‌	mouse
*Cd74^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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