Idh2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial

GeneMGI:96414Synonyms: Idh-2, IDPm

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Hematopoietic system

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

13Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes



decreased mean corpuscular hemoglobin	1 supporting dataset	Idh2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.44x10^-6
increased hemoglobin content	1 supporting dataset	Idh2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.77x10^-5
decreased mean corpuscular volume	1 supporting dataset	Idh2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.01x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Idh2.

Associated images

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Histopathology

There is no histopathology data found for Idh2.

IMPC related publications

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External links

No external links available for Idh2.

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*Idh2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Idh2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Idh2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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