Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble

GeneMGI:96413Synonyms: Idh-1, IDPc, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Idh1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Idh1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Idh1.

Associated images

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Histopathology

There is no histopathology data found for Idh1.

IMPC related publications

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External links

No external links available for Idh1.

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*Idh1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Idh1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Idh1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Idh1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Idh1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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