Id3 | inhibitor of DNA binding 3

GeneMGI:96398Synonyms: bHLHb25, Idb3, +1 more

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:21Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged spleen	2 supporting datasets	Id3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	2.79x10^-5
small testis	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Id3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal freezing behavior	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	4.67x10^-5
decreased brain size	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cornea opacity	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	9.98x10^-6
increased startle reflex	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	1.74x10^-5
microphthalmia	2 supporting datasets	Id3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased mean platelet volume	1 supporting dataset	Id3^em1(IMPC)Mbp	homozygote	Early adult	8.62x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Id3.

Associated images

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Histopathology

There is no histopathology data found for Id3.

IMPC related publications

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External links

No external links available for Id3.

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*Id3^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Id3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Id3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Id3^{tm415703(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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