Hsp90aa1 | heat shock protein 90, alpha (cytosolic), class A member 1

GeneMGI:96250Synonyms: hsp4, Hsp89, +3 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Growth/size/body region Behavior/neurological Skeleton Craniofacial

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	5.54x10^-5
abnormal snout morphology	2 supporting datasets	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	1.24x10^-5
increased grip strength	2 supporting datasets	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	1.28x10^-8
male infertility	1 supporting dataset	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal incisor morphology	1 supporting dataset	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	9.85x10^-6
abnormal cranium morphology	1 supporting dataset	Hsp90aa1^{tm1(KOMP)Wtsi}	homozygote	Early adult	2.05x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hsp90aa1.

Associated images

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Histopathology

There is no histopathology data found for Hsp90aa1.

IMPC related publications

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External links

No external links available for Hsp90aa1.

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*Hsp90aa1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Hsp90aa1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell mouse

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