Hsf1 | heat shock factor 1
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues
| abnormal retina morphology | 1 supporting dataset | Hsf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.79x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Hsf1tm1.1(KOMP)Vlcg | homozygote | E18.5 | N/A * | ||
| abnormal sleep behavior | 1 supporting dataset | Hsf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.89x10-5 | ||
| decreased circulating glucose level | 1 supporting dataset | Hsf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.42x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Hsf1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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External links
No external links available for Hsf1.
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| Hsf1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Hsf1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Hsf1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Hsf1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |